2-deoxy-D-Glucose-13C6

SKU T35683-1 mg Category Brand:

Price range: 141 CAD through 1,176 CAD

Products Details

Product Description

– 2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B osteosarcoma cells cultured under hypoxic conditions when used at a concentration of 2 mg/ml.4,5

Web ID

– T35683

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C5C(13)H12O5

References

– Kang, H.T., and Hwang, E.S.2-Deoxyglucose: An anticancer and antiviral therapeutic, but not any more a low glucose mimeticLife Sci.78(12)1392-1399(2006)

CAS Number

– 201612-55-7

Molecular Weight

– C5C(13)H12O5

SMILES

– #N/A

Pathway

– Others

Product type

– Isotope products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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