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2′,2′-Difluorodeoxyuridine
SKU
HY-138253-Get quote
Category Reference compound
Tags Cancer, Drug Metabolite, Metabolic Enzyme/Protease
Products Details
Product Description
– 2′,2′-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2′,2′-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro[1].
Web ID
– HY-138253
Shipping
– Room temperature
Molecular Formula
– C9H10F2N2O5
References
– [1]Pauwels B, et al. The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro. Cancer Chemother Pharmacol. 2006 Aug;58(2):219-28.
CAS Number
– 114248-23-6
Molecular Weight
– 264.18
SMILES
– O=C(N1)N([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)C=CC1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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