16,16-Dimethyl prostaglandin E2

SKU HY-106420-10 mg (26.28 mM * 1 mL in Methyl acetate) Category Tags , ,

$320$2,650

Products Details

Product Description

– 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway[1][2].

Web ID

– HY-106420

Storage Temperature

– Solution, -20°C, 2 years

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H36O5

References

– [1]Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.|[2]Roulis M, et al. Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4658-67.

CAS Number

– 39746-25-3

Molecular Weight

– 380.52

Compound Purity

– 98.0

SMILES

– CCCCC(C)([C@@H](/C=C/[C@@H]1[C@@H](C/C=CCCCC(O)=O)C(C[C@H]1O)=O)O)C

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Prostaglandin Receptor

Isoform

– EP

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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