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Products Details
Product Description
– 13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].
Web ID
– HY-129240S
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H23D3O3
References
– [1]A E Stuck, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989 Mar; 27(3): 301–304.|[2]Berbis P, et al. Residual plasma concentrations of acitretin (Ro 10-1670) and its metabolite (Ro 13-7652) after chronic administration. Dermatologica. 1988;177(4):244-6.
CAS Number
– 1185241-03-5
Molecular Weight
– 329.45
SMILES
– O=C(/C=C(C=CC=C(C=CC1=C(C=C(C(C)=C1C)OC([2H])([2H])[2H])C)C)C)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Isotope-Labeled Compounds
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
