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Products Details
Product Description
– 12-Oxocalanolide A (compound 6) is a potent inhibitor of reverse transcriptase from human immunodeficiency virus type 1 (HIV-1) with an IC50 and EC50 of 2.8 and 12 μM, respectively. 12-Oxocalanolide A is the analogue of Calanolide[1].
Web ID
– HY-N1034
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C22H24O5
References
– [1]Zembower DE, et al. Structural analogues of the calanolide anti-HIV agents. Modification of the trans-10,11-dimethyldihydropyran-12-ol ring (ring C). J Med Chem. 1997;40(6):1005-1017.
CAS Number
– 161753-49-7
Molecular Weight
– 368.42
SMILES
– O=C1C=C(CCC)C2=C3C(C=CC(C)(C)O3)=C4C(C([C@H](C)[C@@H](C)O4)=O)=C2O1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
