12-Oxo phytodienoic acid

$535

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Products Details

Product Description

– 12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in LPS-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research[1].

Web ID

– HY-118828

Storage Temperature

– Solution, -20°C, 2 years

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C18H28O3

References

– [1]Taki-Nakano N, et al. 12-oxo-phytodienoic acid, a plant-derived oxylipin, attenuates lipopolysaccharide-induced inflammation in microglia. Biochem Biophys Res Commun. 2016 May 13;473(4):1288-1294.

CAS Number

– 85551-10-6

Molecular Weight

– 292.41

Compound Purity

– 99.50

SMILES

– O=C(O)CCCCCCC[C@H]1C=CC([C@H]1C/C=CCC)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– NF-κB;p38 MAPK

Pathway

– MAPK/ERK Pathway;NF-κB

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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