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Products Details
Product Description
– 10-DEBC hydrochloride is a selective Akt inhibitor, with an IC50 of 1.28 μM. 10-DEBC hydrochloride is a novel anti-TB compound[1][2].
Web ID
– HY-100654
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H26Cl2N2O
References
– [1]Wei Li, et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Medicinal Chemistry Communications.|[2]Hyo-Won Han, et al. Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages. Stem Cell Reports. 2019 Dec 10;13(6):980-991.
CAS Number
– 925681-41-0
Molecular Weight
– 381.34
SMILES
– CCN(CC)CCCCN1C2=C(C=CC=C2)OC3=CC=C(Cl)C=C13.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Akt;Bacterial
Pathway
– Anti-infection;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
