1-Hydroxy-ibuprofen

$180$450

Products Details

Product Description

– 1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P. australis[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].

Web ID

– HY-136592

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C13H18O3

References

– [1]Yujie He, et al. Metabolism of Ibuprofen by Phragmites australis: Uptake and Phytodegradation. Environ Sci Technol. 2017 Apr 18;51(8):4576-4584.|[2]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

CAS Number

– 53949-53-4

Molecular Weight

– 222.28

SMILES

– O=C(O)C(C)C1=CC=C(C(O)C(C)C)C=C1

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– COX

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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