1-(2′-Deoxy-5′-O-DMT-2′-fluoro-b-D-arabinofuranosyl)thymine 3′-CE phosphoramidite

Products Details

Product Description

– 1-(2′-Deoxy-5′-O-DMT-2′-fluoro-b-D-arabinofuranosyl)thymine 3′-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Web ID

– HY-154604

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C40H48FN4O8P

References

– [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

CAS Number

– 208193-48-0

Molecular Weight

– 762.80

SMILES

– O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]2F

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Oligonucleotides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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