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Product Description
– β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].
Web ID
– HY-148524
Shipping
– Room temperature
Molecular Formula
– C43H56BrN3O7
References
– [1]WEN SHOUMING, et al. CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE. WO2018108089. 2018.
CAS Number
– 2230520-62-2
Molecular Weight
– 806.82
SMILES
– O[C@@H](C1=C2C(NC(C=C2)=O)=C(C=C1)O)CNCCCOC(C=C3)=CC=C3OCCC[N+]45C[C@H](C(CC5)CC4)OC[C@@](C6CCCC6)(C7=CC=CC=C7)O.[Br-]
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
