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Products Details
Product Description
– α-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts[1].
Web ID
– HY-118517
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H29NO2
References
– [1]Phillips DH, et al. alpha-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes. Cancer Res. 1994 Nov 1;54(21):5518-22.
CAS Number
– 97151-02-5
Molecular Weight
– 387.51
SMILES
– CC(/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
