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Products Details
Product Description
– α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive and orally active α-glucosidase inhibitor with an IC50 value of 3.07 μM. α-Glucosidase-IN-32 complex with α-glucosidase through hydrogen bonds and hydrophobic interactions, led to changes in the conformation and secondary strictures of α-glucosidase and further the inhibition of the enzymatic activity. α-Glucosidase-IN-32 can be used for diabetic disease research[1].
Web ID
– HY-156078
Shipping
– Room temperature
Molecular Formula
– C32H22N4OS
References
– [1]Xiao D, et al. Identification of 1,3,4-oxadiazolyl-containing β-carboline derivatives as novel α-glucosidase inhibitors with antidiabetic activity. Eur J Med Chem. 2023 Sep 7;261:115795.
Molecular Weight
– 510.61
SMILES
– C1(C2=NC(C3=NN=C(SCC4=CC=CC=C4C5=CC=CC=C5)O3)=CC6=C2NC7=CC=CC=C67)=CC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
