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Products Details
Product Description
– α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study[1].
Web ID
– HY-155105
Shipping
– Room temperature
Molecular Formula
– C20H19N7O2
References
– [1]Yousefnejad F, et al. Design, synthesis, in vitro, and in silico evaluations of benzo[d]imidazole-amide-1,2,3-triazole-N-arylacetamide hybrids as new antidiabetic agents targeting α-glucosidase. Sci Rep. 2023;13(1):12397.
Molecular Weight
– 389.41
SMILES
– O=C(NCC1=CN(CC(NC2=CC(C)=CC=C2)=O)N=N1)C3=NC4=CC=CC=C4N3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
