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Products Details
Product Description
– α-Amylase/α-Glucosidase-IN-5 (compound 4l) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50s of 5.96 μM and 1.62 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity[1].
Web ID
– HY-149557
Shipping
– Room temperature
Molecular Formula
– C30H27BrN3O3P
References
– [1]Zareei S, et al. Discovery of novel 4,5-diphenyl-imidazol-α-aminophosphonate hybrids as promising anti-diabetic agents: Design, synthesis, in vitro, and in silico enzymatic studies. Bioorg Chem. 2023 Sep 9;141:106846.. .
Molecular Weight
– 588.43
SMILES
– BrC1=CC(C(P(OC)(OC)=O)NC2=CC=C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)N3)C=C2)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Amylases;Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
