What are epigenetics research compounds?

Epigenetics research compounds are small molecules that modulate heritable changes in gene expression without altering DNA sequence. They target histone-modifying enzymes (HDACs, HATs, methyltransferases, demethylases), DNA methyltransferases, and epigenetic reader proteins (bromodomains, chromodomains). These tools are essential for studying chromatin biology, gene regulation, and epigenetic mechanisms in disease.

What HDAC inhibitors do you offer?

We provide pan-HDAC and class-selective HDAC inhibitors targeting Class I (HDAC1, 2, 3, 8), Class II (HDAC4, 5, 6, 7, 9, 10), Class III (sirtuins), and Class IV (HDAC11). These compounds are widely used in chromatin remodeling studies, gene expression analysis, and cancer epigenetics research.

What histone methyltransferase and demethylase modulators are available?

Our collection includes inhibitors of histone methyltransferases (EZH2, DOT1L, G9a, SUV39H1) and histone demethylases (LSD1, JMJD, KDM families). These tools enable researchers to study histone methylation marks (H3K4, H3K9, H3K27, H3K36) and their roles in gene activation, silencing, and chromatin structure.

Do you carry DNMT inhibitors and DNA methylation tools?

Yes. We offer DNMT1, DNMT3A, and DNMT3B inhibitors as well as compounds affecting DNA demethylation (TET enzymes). These are used to study CpG methylation, genomic imprinting, X-chromosome inactivation, and aberrant DNA methylation patterns in cancer research.

What BET bromodomain and epigenetic reader compounds do you offer?

We carry BET family inhibitors (BRD2, BRD3, BRD4, BRDT), PROTAC degraders of BET proteins, and compounds targeting other reader domains (chromodomains, PHD fingers, Tudor domains). These tools are used to study super-enhancer biology, transcriptional regulation, and epigenetic drug discovery.

Are these compounds suitable for in vitro epigenetic assays?

Yes. Our epigenetics compounds are optimized for histone modification ELISAs, ChIP assays, methylation-specific PCR, reporter gene assays, and high-throughput screening. All compounds include CAS numbers, purity certificates, and technical datasheets for assay validation.

How do I select the right epigenetics compound?

Use our interactive product browser to filter by target (HDAC, HMT, DNMT, BET, etc.), search by CAS number, or browse by target class. Each product includes potency data and selectivity information. Contact our team for compound selection guidance.

Do you ship epigenetics research compounds internationally?

Yes. We ship to Canada and Europe with 5-10 business day delivery for in-stock items, and offer worldwide shipping. All compounds are for research use only and shipped with proper documentation including certificates of analysis.

Epigenetics Research Compounds | HDAC & Histone Modulators | Immunomart

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Epigenetics

Epigenetics Research Compounds

Discover 2,076+ research-grade compounds targeting epigenetic mechanisms, including HDAC inhibitors, histone methyltransferase modulators, DNMT inhibitors, and BET bromodomain antagonists. Essential tools for chromatin biology, gene regulation, and epigenetic drug discovery.

Browse All 2,076+ Compounds ← Back to All Pathways

2,076+

Epigenetics Compounds

126+

Targets

💰

Competitive Pricing

🌎

Worldwide Shipping

Featured Epigenetics Research Compounds

AICAR

SKU: T1477

CAS: 2627-69-2MW: 258.23Target: HDAC

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MBM-55

SKU: T11960

CAS: 2083622-09-5MW: 498.55Target: Histone Methyltransferase

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CM-579

SKU: T10840L

CAS: 1846570-40-8MW: 492.65Target: Epigenetic Reader Domain

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Vafidemstat

SKU: T17211

CAS: 1357362-02-7MW: 336.39Target: Aurora Kinase

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Procainamide hydrochloride

SKU: T0018

CAS: 614-39-1MW: 271.79Target: MRP

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Miltefosine

SKU: T0033

CAS: 58066-85-6MW: 407.57Target: P-gp

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Acetaminophen

SKU: T0065

CAS: 103-90-2MW: 151.16Target: Adenosine Receptor

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Oltipraz

SKU: T0153

CAS: 64224-21-1MW: 226.34Target: Wnt/beta-catenin

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Mitoxantrone dihydrochloride

SKU: T0158

CAS: 70476-82-3MW: 517.4Target: Endogenous Metabolite

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Cyproheptadine hydrochloride sesquihydrate

SKU: T0174

CAS: 41354-29-4MW: 341.88Target: 5-HT Receptor

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Tilorone dihydrochloride

SKU: T0244

CAS: 27591-69-1MW: 483.47Target: Antibacterial

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Citric acid trilithium salt tetrahydrate

SKU: T0256

CAS: 6080-58-6MW: 281.98Target: Autophagy

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Browse by Target

Understanding Epigenetic Mechanisms

Histone Acetylation & HDACs

Histone acetylation by HATs (histone acetyltransferases) opens chromatin and activates gene transcription, while HDACs (histone deacetylases) remove acetyl marks to silence genes. HDAC inhibitors are among the most widely used epigenetic tools, enabling studies of chromatin dynamics, gene regulation, and cell differentiation in research models.

Histone Methylation

Histone methyltransferases (HMTs) and demethylases write and erase methyl marks on histone tails, creating a complex code that regulates gene expression. Key targets include EZH2 (H3K27me3), G9a (H3K9me2), DOT1L (H3K79me), and LSD1/KDM demethylases. Selective inhibitors dissect how specific methylation marks control transcriptional programs.

DNA Methylation & DNMTs

DNA methyltransferases (DNMT1, DNMT3A, DNMT3B) add methyl groups to cytosine residues in CpG dinucleotides, typically silencing gene expression. DNMT inhibitors and TET enzyme modulators are essential for studying DNA methylation patterns, genomic imprinting, and epigenetic reprogramming in development and disease research.

Epigenetic Readers & BET Proteins

Reader proteins recognize and bind specific histone modifications to recruit transcriptional machinery. BET bromodomain proteins (BRD2, BRD3, BRD4) read acetylated histones and are key regulators of super-enhancer-driven gene expression. BET inhibitors and PROTACs are powerful tools for studying transcriptional regulation and gene control mechanisms.

Epigenetics and chromatin biology research

Why Choose Immunomart for Epigenetics Research?

🧪

2,076+ Compounds

One of the largest collections of epigenetics research compounds, covering histone modification, DNA methylation, and chromatin reader pathways.

📈

Research-Grade Quality

All compounds include CAS numbers, purity certificates, and technical datasheets. Optimized for ChIP, methylation assays, and compound screening.

💰

Competitive Pricing

Access premium epigenetics research compounds at competitive prices. Volume discounts and custom panel pricing available for screening programs.

🚚

Fast Shipping

US: 2–5 business days for in-stock items. Canada and Europe: 5–10 business days. Worldwide shipping available with proper documentation.

Epigenetics Research Compounds