SB399885
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SB399885

SKU T19669-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 142 CAD through 1,792 CAD

Products Details

Product Description

– SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).

Web ID

– T19669

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H21Cl2N3O4S

References

– Abraham R, Nirogi R, Shinde A, Benade VS. Therapeutic Potential of 5-HT6 Antagonist SB399885 in Traumatic Stress Disorder. Drug Res (Stuttg). 2015 Aug;65(8):442-5. doi: 10.1055/s-0034-1390418. Epub 2014 Oct 13. PubMed PMID: 25310249.

CAS Number

– 402713-80-8

Molecular Weight

– C18H21Cl2N3O4S

Compound Purity

– 0.9894

SMILES

– O(C)C1=C(C=C(S(NC2=C(OC)C(Cl)=CC(Cl)=C2)(=O)=O)C=C1)N3CCNCC3

Target

– Autophagy|||Apoptosis|||Ferroptosis

Pathway

– GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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