SEMA4B Protein, Mouse, Recombinant (His)

SKU TMPK-01034-100 μg Category Brand:

Price range: 630 CAD through 2,512 CAD

Products Details

Product Description

– Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.

Web ID

– TMPK-01034

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Jian H, et al. SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo. Cell Signal. 2015 Jun;27(6):1208-13. doi: 10.1016/j.cellsig.2015.02.027. Epub 2015 Mar 4. PMID: 25746385.

Molecular Weight

Compound Purity

– > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC

Product type

– Recombinant-Protein

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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