TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)

SKU TMPK-00277-100 μg Category Brand:

Price range: 555 CAD through 2,240 CAD

Products Details

Product Description

– DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Web ID

– TMPK-00277

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Zheng D, et al. Is death receptor 4 or 5 a good traget for cancer antibody therapy?[J]. New Biotechnology, 2012, 29:S114.

Molecular Weight

Product type

– Recombinant-Protein

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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