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SI-113
Price range: 61 CAD through 922 CAD
Products Details
Product Description
– SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.
Web ID
– T9589
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H24N6O
Citations
– 1. Xiong Y, Li C, Yu J, et al.A novel trifluoromethyl quinoline derivative targeting SGK1 inducing autophagy and apoptosis via regulating mTOR/FOXO3a pathway in glioblastoma.Arabian Journal of Chemistry.2024: 105909.
References
– Matteoni S, et al. The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells. J Exp Clin Cancer Res. 2019 May 17;38(1):202.
CAS Number
– 1392816-46-4
Molecular Weight
– C23H24N6O
Compound Purity
– 0.9881
SMILES
– C(=CC1=CC=CC=C1)N2C=3C(=C(NCCC4=CC=CC=C4)N=C(NCCO)N3)C=N2
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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