M435-1279

SKU T9500-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 1,059 CAD

Products Details

Product Description

– M435-1279 is a UBE2T inhibitor that blocks UBE2T-mediated degradation of RACK1, thereby inhibiting the hyperactivation of the Wnt/β-catenin signaling pathway.

Web ID

– T9500

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H17N3O5S2

References

– Yu Z, Jiang X, Qin L, Deng H, Wang J, Ren W, Li H, Zhao L, Liu H, Yan H, Shi W, Wang Q, Luo C, Long B, Zhou H, Sun H, Jiao Z. A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination. Oncogene. 2021 Feb;40(5):1027-1042. doi: 10.1038/s41388-020-01572-w. Epub 2020 Dec 15. Erratum in: Oncogene. 2021 Apr;40(14):2622-2623. PMID: 33323973; PMCID: PMC7862066.

CAS Number

– 1359431-16-5

Molecular Weight

– C18H17N3O5S2

Compound Purity

– 0.9716

SMILES

– NS(=O)(=O)c1ccc(NC(=O)c2c(O)c3c4CCCCc4sc3[nH]c2=O)cc1

Pathway

– Ubiquitination

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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