ASK1-IN-2

SKU T9377-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 109 CAD through 1,712 CAD

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1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Product Description

– ASK1-IN-2 is a potent, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. It has potential therapeutic applications for ulcerative colitis[1].

Web ID

– T9377

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H17FN6O

References

– Hou S, et, al. Structure-based discovery of 1H-indole-2-carboxamide derivatives as potent ASK1 inhibitors for potential treatment of ulcerative colitis. Eur J Med Chem. 2020 Dec 24;211:113114.

CAS Number

– 2541792-70-3

Molecular Weight

– C19H17FN6O

Compound Purity

– 0.9936

SMILES

– CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccc(F)cc3[nH]2)n1

Pathway

– Apoptosis|||MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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