TLR8 agonist 9
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TLR8 agonist 9

SKU T88096-25 mg Category Brand:

Price range: 4,352 CAD through 7,840 CAD

Products Details

Product Description

– TLR8 agonist9 (Compound II-77) functions as an agonist for Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. This compound is stable in human and mouse plasma and effectively induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist9 demonstrates significant antitumor activity, achieving a tumor growth inhibition (TGI) rate of 97%.

Web ID

– T88096

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C38H43N7O8

CAS Number

– 3034750-61-0

Molecular Weight

– C38H43N7O8

SMILES

– O=C1C=CC(=O)N1CC2OCC(C(=O)N3CC4=CC(=CN=C4CC3)NC(=O)C5(C=6C=CC=7C=C(C(=O)N(CCO)CCC)CC(=NC7C6)N)CC5)CO2

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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