GPR183 antagonist-2

SKU T86519-10 mg Category Brand:

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Products Details

Product Description

– GPR183 antagonist-2 (compound 32), a selective antagonist of GPR183, exhibits excellent water solubility and pharmacokinetic properties. This compound effectively diminishes paw and joint swelling, and reduces gene expression of pro-inflammatory cytokines (MCP-1, MMPs, and VEGF) in a dose-dependent manner within a collagen-induced arthritis (CIA) mouse model. GPR183 antagonist-2 is applicable in researching autoimmune diseases [1].

Web ID

– T86519

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H18F2N4O5

CAS Number

– 2924063-98-7

Molecular Weight

– C20H18F2N4O5

SMILES

– C(=C/C(=O)N1CCN(C(=O)C=2C=NC(OC)=NC2)CC1)C=3C=C4C(=CC3)OC(F)(F)O4

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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