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Product Description
– 2′(3′)-O-Anthraniloylguanosine-5′-O-triphosphate (2′-ANT-GTP) and 3′-ANT-GTP are fluorescent derivatives of GTP that exhibit spontaneous isomerization. 2′(3′)-ANT-GTP features an emission peak at 428 nm when excited at 330 nm in aqueous conditions. It functions as an inhibitor of several adenylyl cyclases, notably mammalian adenylyl cyclase 1 (AC1; Ki = 10 nM with manganese), inhibits B. anthracis adenylyl cyclase toxin edema factor (Kis = 4.1 and 13 µM with manganese and magnesium, respectively), and B. pertussis adenylyl cyclase toxin CyaA (Ki = 29 µM with manganese).
Web ID
– T83843
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H17N6O15P3.4Na
Molecular Weight
– C17H17N6O15P3.4Na
SMILES
– O[C@@H]1[C@H](OC(C2=C(N)C=CC=C2)=O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@H]1N3C(NC(N)=NC4=O)=C4N=C3.O[C@@H]5[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N6C(NC(N)=NC7=O)=C7N=C6)[C@@H]5OC(C8=C(N)C=CC=C8)=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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