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PROTAC EGFR degrader 7 diTFA

SKU T81380-5 mg Category Brand:

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Products Details

Product Description

– PROTAC EGFR degrader 7 (compound 13b) is a potent, selective, CRBN-recruiting EGFRL858R/T790M degrader with a DC50 of 13.2 nM. It effectively inhibits NCI-H1975 cell proliferation with an IC50 of 46.82 nM, induces apoptosis, and causes G2/M phase arrest. This compound shows antitumor activity and is applicable in non-small cell lung cancer (NSCLC) research.

Web ID

– T81380

Storage Temperature

– -20℃

Shipping

– Blue Ice

Pathway

– PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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