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UC-764864
Price range: 171 CAD through 2,336 CAD
Products Details
Product Description
– UC-764864 is a selective UBE2N inhibitor that blocks E1-UBE2N thioester transfer, inhibits innate immune signaling and induces cytotoxic effects in MDS/AML cell lines and primary cells. In addition, UC-764864 reduces the ubiquitination status of UBE2N and can be used to study leukemia.
Web ID
– T79133
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H18N2OS
References
– Barreyro L, et al. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Sci Transl Med. 2022 Mar 9;14(635):eabb7695.
CAS Number
– 278806-03-4
Molecular Weight
– C19H18N2OS
Compound Purity
– 0.993
SMILES
– O=C(C=CSC1=NC=2C=C(C=CC2N1)C)C3=CC=C(C=C3)CC
Pathway
– Ubiquitination
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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