SIKs-IN-1
Add to CompareAdded to Compare

Download Files:

SIKs-IN-1

SKU T78762-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, functions as an inhibitor of Salt-inducible kinases (SIKs), which play a role in M1/M2 macrophage polarization linked to inflammation. By inhibiting SIK activity, this compound increases anti-inflammatory cytokine IL-10 and decreases pro-inflammatory cytokine IL-12, demonstrating significant anti-inflammatory efficacy in a DSS-induced colitis model [1].

Web ID

– T78762

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H31F2N7O

CAS Number

– 2927557-06-8

Molecular Weight

– C27H31F2N7O

SMILES

– C(NC1=C(C)C=CC=C1F)(=O)C=2C(NC3CCC3)=NC(NC4=CC(F)=C(C=C4)N5CCN(C)CC5)=NC2

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Mexenone
Mexenone Price range: 48 CAD through 157 CAD
1 mL * 10 mM (in DMSO)100 mg200 mg

1000 in stock

Select options
Mecarbinate
Mecarbinate Price range: 46 CAD through 56 CAD
1 g1 mL * 10 mM (in DMSO)

1000 in stock

Add to cart
Methylene Blue trihydrate
Methylene Blue trihydrate 58 CAD

1000 in stock

Select options
Atenolol Hydrochloride
Atenolol Hydrochloride Price range: 2,432 CAD through 4,000 CAD
100 mg25 mg50 mg

1000 in stock

Select options
4-Ethoxycoumarin
4-Ethoxycoumarin 46 CAD
1 g1 mL * 10 mM (in DMSO)

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });