Iberdomide
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Iberdomide

SKU T7791-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 3,024 CAD

Products Details

Product Description

– Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).

Web ID

– T7791

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H27N3O5

Citations

– 1. Li P, Hu X, Fan Z, et al.Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.Journal of Hematology & Oncology.2024, 17(1): 77.

References

– Matyskiela M E , Zhang W , Man H W , et al. A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos[J]. Journal of Medicinal Chemistry, 2017:acs.jmedchem.6b01921.

CAS Number

– 1323403-33-3

Molecular Weight

– C25H27N3O5

Compound Purity

– 0.9701

SMILES

– O(CC1=CC=C(CN2CCOCC2)C=C1)C3=C4C(C(=O)N(C4)[C@@H]5C(=O)NC(=O)CC5)=CC=C3

Pathway

– PROTAC|||Apoptosis

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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