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Products Details
Product Description
– A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.
Web ID
– T7616
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H60N12O11
Citations
– 1. Yang S, Cao J, Wang Y, et al.Small Intestinal Endocrine Cell Derived Exosomal ACE2 Protects Islet β-Cell Function by Inhibiting the Activation of NLRP3 Inflammasome and Reducing β-Cell Pyroptosis.International Journal of Nanomedicine.2024: 4957-4976.
2. He C, Li R, Zhang J, et al.Sivelestat protects against acute lung injury by up-regulating angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas receptors.Journal of Thoracic Disease.2024, 16(9).
References
– Yan W F , Xue J J , Yang H Y , et al. [Effects and related mechanism of angiotensin-(1-7) on Toll-like receptor 4-mediated oxidative stress in human umbilical vein endothelial cells].[J]. Zhonghua Xin Xue Guan Bing Za Zhi, 2017, 45(3):223.
CAS Number
– 159432-28-7
Molecular Weight
– C39H60N12O11
SMILES
– [H][C@](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C)C(O)=O
Pathway
– Endocrinology/Hormones
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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