GSK3735967
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GSK3735967

SKU T74887-5 mg Category Brand:

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Products Details

Product Description

– GSK3735967 is a selective, reversible, non-nucleoside inhibitor targeting DNMT1, demonstrating an IC50 value of 40 nM. It features a planar dicyanopyridine core designed to specifically interact with DNMT1-bound hemimethylated CpG dinucleotides. Additionally, GSK3735967 possesses three binding sites, with one uniquely capable of binding to histone H4K20me3 [1] [2].

Web ID

– T74887

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H31N7OS

CAS Number

– 2170136-86-2

Molecular Weight

– C25H31N7OS

SMILES

– C(#N)C1=C(N=C(SCC2=CC=C(CNC(CN)=O)C=C2)C(C#N)=C1CC)N3CCN(C)CCC3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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