360A
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360A

SKU T7409-1 mg Category Brand:

Price range: 155 CAD through 1,792 CAD

Products Details

Product Description

– 360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).

Web ID

– T7409

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H23N5O2

Citations

– 1. Liu T, Wu Y, Qin L, et al.Nonselective Intercalation of G-Quadruplex-Targeting Ligands into Double-Stranded DNA Quantified by Single-Molecule Stretching.The Journal of Physical Chemistry B.2023 2. Zhang Y, Cheng Y, Luo Q, et al.Distinguishing G-Quadruplexes Stabilizer and Chaperone for c-MYC Promoter G-Quadruplexes through Single-Molecule Manipulation.Journal of the American Chemical Society.2024

References

– Hwang I , Mailliet P , Hossard V , et al. Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA)[J]. Molecules, 2019, 24(3).

CAS Number

– 794458-56-3

Molecular Weight

– C27H23N5O2

Compound Purity

– 0.9868

SMILES

– C[N+]=1C2=C(C=C(NC(=O)C=3N=C(C(NC4=CC5=C([N+](C)=C4)C=CC=C5)=O)C=CC3)C1)C=CC=C2

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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