RI-962
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RI-962

SKU T73493-1 mg Category Brand:

Price range: 469 CAD through 4,000 CAD

Products Details

Product Description

– RI-962 is a potent and selective inhibitor of RIPK1 that dose-dependently protects cells from necrotic apoptosis induced by TNFα, Smac mimics, and Z-VAD-FMK by inhibiting RIPK1, RIPK3, and MLKL phosphorylation with EC50=10.0 nM~17.8 nM, and improves survival in mice in two models of inflammation.

Web ID

– T73493

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H28N6O2

CAS Number

– 2763831-53-2

Molecular Weight

– C28H28N6O2

Compound Purity

– 0.9939

SMILES

– O=C(NC(C=1C=CC=CC1)C)C2=CN(C=3C=CC(=CC23)C=4C=CN5N=C(N=C5C4)NC(=O)C(C)C)C

Pathway

– Apoptosis|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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