RO5461111
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RO5461111

SKU T73220-25 mg Category Brand:

Price range: 5,229 CAD through 7,677 CAD

Products Details

Product Description

– RO5461111, a highly specific and orally active Cathepsin S antagonist, exhibits potent inhibitory effects with IC50 values of 0.4 nM (human Cathepsin S) and 0.5 nM (murine Cathepsin S), respectively. It effectively suppresses the activation of antigen-specific T cells and B cells, and can ameliorate pulmonary inflammation and lupus nephritis.

Web ID

– T73220

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H24F6N4O4S

CAS Number

– 1252637-46-9

Molecular Weight

– C27H24F6N4O4S

SMILES

– C(=O)(C1(C(F)(F)F)CC1)N2[C@H](C(NC3(C#N)CC3)=O)C[C@@H](S(=O)(=O)C4=C(C(F)(F)F)C=C(C=C4)C=5C=C(C)N=CC5)C2

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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