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Oxaliplatin-d10
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.7 µM, respectively). It reduces tumor growth in an HCCLM3 mouse xenograft model when administered at doses of 5 or 10 mg/kg once per week. Formulations containing oxaliplatin have been used in the treatment of advanced colorectal cancer and as adjuvants in stage III colon cancer.
Web ID
– T71401
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C8H4D10N2O4Pt
CAS Number
– 1132819-16-9
Molecular Weight
– C8H4D10N2O4Pt
SMILES
– O=C1[O-][Pt+2]2([NH2][C@]3([C@]([NH2]2)(C(C(C(C3([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])[2H])[2H])[O-]C1=O
Product type
– Isotope products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
