Vps34-IN-1
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Vps34-IN-1

SKU T7015-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 850 CAD

Products Details

Product Description

– Vps34-IN-1 (VPS34-IN1) is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM in vitro, which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.

Web ID

– T7015

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H24ClN7O

Citations

– 1. Zhang H, Cui Z, Cheng D, et al. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis. Autophagy. 2021 Oct;17(10):3030-3047

References

– Bago R, et al. Biochem J. 2014 Nov 1;463(3):413-27.

CAS Number

– 1383716-33-3

Molecular Weight

– C21H24ClN7O

Compound Purity

– 0.9704

SMILES

– CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccnc(Cl)c2)n1

Pathway

– Autophagy|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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