Download Files:
UNC2025
Price range: 53 CAD through 590 CAD
Products Details
Product Description
– UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
Web ID
– T7007
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H40N6O
Citations
– 1. Wei S, Guan G, Luan X, et al.NLRP3 inflammasome constrains liver regeneration through impairing MerTK-mediated macrophage efferocytosis.Science Advances.2025, 11(1): eadq5786.
References
– Zhang W, et al. J Med Chem. 2014, 57(16), 7031-7041.
CAS Number
– 1429881-91-3
Molecular Weight
– C28H40N6O
Compound Purity
– 0.9953
SMILES
– CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
