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Ulixertinib
Price range: 54 CAD through 1,371 CAD
Products Details
Product Description
– Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.
Web ID
– T7005
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H22Cl2N4O2
Citations
– 1. Caiola E, Iezzi A, Tomanelli M, et al. LKB1 deficiency renders non-small-cell lung cancer cells sensitive to ERK inhibitors.: ERK inhibitors in LKB1 mutated NSCLC. Journal of Thoracic Oncology. 2019
2. Caiola E, Iezzi A, Tomanelli M, et al. LKB1 Deficiency Renders NSCLC Cells Sensitive to ERK Inhibitors. Journal of Thoracic Oncology. 2020, 15(3): 360-370
References
– Ward RA, et al. J Med Chem. 2015, 58(11), 4790-4801.
CAS Number
– 869886-67-9
Molecular Weight
– C21H22Cl2N4O2
Compound Purity
– 0.9989
SMILES
– CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c(Cl)cn1
Pathway
– MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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