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PCSK9-IN-11
Price range: 75 CAD through 658 CAD
Products Details
Product Description
– PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity, exhibiting inhibitory activity on PCSK9 transcription in HepG2 cells (IC50 = 5.7 μM) and capable of increasing LDL receptor (LDLR) protein levels. PCSK9-IN-11 is applicable for atherosclerosis research.
Web ID
– T67776
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H17ClFN5O3
References
– Qiao MQ, et al. Structure-activity relationship and biological evaluation of xanthine derivatives as PCSK9 inhibitors for the treatment of atherosclerosis. Eur J Med Chem. 2022 Dec 26;247:115047.
Molecular Weight
– C16H17ClFN5O3
Compound Purity
– 0.9837
SMILES
– CN1C(=O)C2=C(N=C(NCCO)N2CC2=C(F)C(Cl)=CC=C2)N(C)C1=O
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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