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TCS7010
Price range: 48 CAD through 1,317 CAD
Products Details
Product Description
– TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
Web ID
– T6767
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H31ClFN7O2
Citations
– 1. Chen H, Hu J, Xiong X, et al.AURKA inhibition induces Ewing’s sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis.Cell Death & Disease.2024, 15(1): 99.
References
– Aliagas-Martin I, et al. J Med Chem, 2009, 52(10), 3300-3307.
CAS Number
– 1158838-45-9
Molecular Weight
– C31H31ClFN7O2
Compound Purity
– 0.9969
SMILES
– CCN1CCN(CC1)C(=O)Cc1ccc(Nc2ncc(F)c(Nc3ccc(cc3)C(=O)Nc3ccccc3Cl)n2)cc1
Pathway
– Apoptosis|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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