Xevinapant
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Xevinapant

SKU T6763-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 2,224 CAD

Products Details

Product Description

– Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.

Web ID

– T6763

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H43N5O4

References

– Cai Q, et al. J Med Chem, 2011, 54(8), 2714-2726.

CAS Number

– 1071992-99-8

Molecular Weight

– C32H43N5O4

Compound Purity

– 0.9956

SMILES

– CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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