A-1155463
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A-1155463

SKU T6748-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 440 CAD

Products Details

Product Description

– A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).

Web ID

– T6748

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C35H32FN5O4S2

Citations

– 1. Devin J, Cañeque T, Lin Y L, et al. Targeting cellular iron homeostasis with ironomycin in diffuse large B cell lymphoma. Cancer Research. 2022 2. Devin J, Cañeque T, Lin Y L, et al. Targeting cellular iron homeostasis with ironomycin in diffuse large B cell lymphomaTargeting cellular iron homeostasis with ironomycin in DLBCL. Cancer Research. 2022

References

– Tao ZF, et al. ACS Med Chem Lett. 2014, 5(10):1088-93.

CAS Number

– 1235034-55-5

Molecular Weight

– C35H32FN5O4S2

Compound Purity

– 0.98

SMILES

– C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3

Pathway

– Apoptosis

Product type

– Peptide

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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