WZ-3146
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WZ-3146

SKU T6733-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,229 CAD

Products Details

Product Description

– WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).

Web ID

– T6733

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H25ClN6O2

References

– Zhou W, et al. Nature, 2009, 462(7276), 1070-1074.

CAS Number

– 1214265-56-1

Molecular Weight

– C24H25ClN6O2

Compound Purity

– 0.9895

SMILES

– CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)cc1

Pathway

– Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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