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SC75741
Price range: 58 CAD through 954 CAD
Products Details
Product Description
– SC75741 is a potent P65 inhibitor with IC50 of 200 nM
Web ID
– T6661
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H23N7O2S2
Citations
– 1. Zhou D, Yang S, Yan H, et al. SC75741, a novel c-Abl inhibitor, promotes the clearance of TDP25 aggregates via ATG5-dependent autophagy pathway. Frontiers in Pharmacology. 2021: 2891.
2. Hu Q, Du H, Ma G, et al. Purification, identification and functional characterization of an immunomodulatory protein from Pleurotus eryngii. Food & Function. 2018, 9(7): 3764-3775
3. Su J, Yin W, Huo M, et al.Induction of apoptosis in glioma cells by lycorine via reactive oxygen species generation and regulation of NF-κB pathways.Naunyn-Schmiedeberg’s Archives of Pharmacology.2023: 1-9.
4. Geng R, Zhao Y, Xu W, et al.SIRPB1 regulates inflammatory factor expression in the glioma microenvironment via SYK: functional and bioinformatics insights.Journal of Translational Medicine.2024, 22(1): 338
5. Zheng M, Zhai Y, Yu Y, et al.TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response.Cell Metabolism.2024
References
– Leban J, et al. Bioorg Med Chem Lett. 2007, 17(21), 5858-5862.
CAS Number
– 913822-46-5
Molecular Weight
– C29H23N7O2S2
Compound Purity
– 0.9982
SMILES
– O=C(Nc1nc2ccc(cc2[nH]1)C(=O)c1ccccc1)c1csc(n1)C1CCN(CC1)c1ncnc2ccsc12
Pathway
– Microbiology/Virology|||NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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