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N6-methyladenosine
Price range: 66 CAD through 258 CAD
Products Details
Product Description
– N6-Methyladenosine is a methylated adenine residue, glycoside is an endogenous uridine product of transfer RNA degradation. It is the most prevalent internal modification of messenger RNA present in all higher eukaryotes and can modify viral RNA with antiviral activity.
Web ID
– T6599
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H15N5O4
Citations
– 1. Zhou L, Tian S, Qin G. RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening. genome biology. 2019, 20(1): 1-23.
2. Zhou L, Tang R, Li X, et al. N6-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner. Genome Biology. 2021, 22(1): 1-32
3. Li B, Zhang M, Sun W, et al.N6‐methyladenosine RNA modification regulates cotton drought response in a Ca2+ and ABA‐dependent manner.Plant Biotechnology Journal.2023
4. Li H, Yu K, Hu H, et al.METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer.Redox Biology.2024: 103087.
5. Su D, Shu P, Hu N, et al.Dynamic m6A mRNA methylation reveals the involvement of AcALKBH10 in ripening‐related quality regulation in kiwifruit.New Phytologist.2024
6. Zhong S, Li X, Li C, et al.SERRATE drives phase separation behaviours to regulate m6A modification and miRNA biogenesis.Nature Cell Biology.2024: 1-15.
7. Tang R, Duan X, Zhou L, et al.The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry.Nature Communications.2024, 15(1): 1-20.
8. Song Z, Yang Q, Dong B, et al.Nanopore RNA direct sequencing identifies that m6A modification is essential for sorbitol-controlled resistance to Alternaria alternata in apple.Developmental Cell.2025
9. Zhou L, Gao G, Tang R, et al.Redox modification of m6A demethylase SlALKBH2 in tomato regulates fruit ripening.Nature Plants.2025: 1-16.
10. FTO Promotes Osteogenic Differentiation of Human BMSCs via Demethylation of TGFB2 m6A Modifications
References
– Aloni Y, et al. J Virol, 1979, 32(1), 52-60.
CAS Number
– 1867-73-8
Molecular Weight
– C11H15N5O4
Compound Purity
– 0.9863
SMILES
– O[C@H]1[C@H](N2C=3C(N=C2)=C(NC)N=CN3)O[C@H](CO)[C@H]1O
Pathway
– Metabolism|||Microbiology/Virology
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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