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Indoximod
Price range: 64 CAD through 142 CAD
Products Details
Product Description
– Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
Web ID
– T6543
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C12H14N2O2
Citations
– 1. Nguyen D J M, Theodoropoulos G, Li Y Y, et al. Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer. Molecular Cancer Research. 2019: molcanres. 0239.2019
References
– Hou DY, et al. Cancer Res. 2007, 67(2), 792-801.
CAS Number
– 110117-83-4
Molecular Weight
– C12H14N2O2
Compound Purity
– 0.995
SMILES
– Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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