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G-418 disulfate
Price range: 67 CAD through 253 CAD
Products Details
Product Description
– G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.
Web ID
– T6512
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H40N4O10·2H2O4S
Citations
– 1. Shao C S, Zhou X H, Miao Y H, et al. In-situ observation of mitochondrial biogenesis as the early event of apoptosis. Iscience. 2021, 24(9): 103038.
2. Yan R, Xie E, Li Y, et al. The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Research. 2022-32（7）P1-4
3. Ye G, Huang M, Li Y, et al. The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway. Acta Pharmaceutica Sinica B. 2021
4. Shao C S, Zhou X H, Miao Y H, et al. In situ observation of mitochondrial biogenesis as the early event of apoptosis. Iscience. 2021, 24(9): 103038
5. Wang W, Zhang M, Huang Z, et al. Knockdown of CXCL5 inhibits the invasion, metastasis and stemness of bladder cancer lung metastatic cells by downregulating CD44. Anti-Cancer Drugs. 2022, 33(1): e103-e112.
6. Wang W, Zhang M, Huang Z, et al. Knockdown of CXCL5 inhibits the invasion, metastasis and stemness of bladder cancer lung metastatic cells by downregulating CD44. Anti-Cancer Drugs. 2022, 33(1): e103-e112.
7. Cheng G, An F, Cao Z, et al.DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway.European Journal of Histochemistry.2023, 67(1).
8. Yin J, Chen J, Hong J H, et al.4EBP1-mediated SLC7A11 protein synthesis restrains ferroptosis triggered by MEK inhibitors in advanced ovarian cancer.JCI insight.2024
9. Multi-Omics Analysis Revealed That TAOK1 Can Be Used as a Prognostic Marker and Target in a Variety of Tumors, Especially in Cervical Cancer
10. Beauvericin suppresses the proliferation and pulmonary metastasis of osteosarcoma by selectively inhibiting TGFBR2 pathway
References
– Delrue I, et al. Determination of the Selection Capacity of Antibiotics for Gene Selection. Biotechnol J. 2018 Aug;13(8):e1700747.
CAS Number
– 108321-42-2
Molecular Weight
– C20H40N4O10·2H2O4S
Compound Purity
– 0.9978
SMILES
– OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O
Pathway
– Microbiology/Virology
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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