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NXPZ-2
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– NXPZ-2 is an orally active Keap1-Nrf2 protein-protein interaction (PPI) inhibitor (Ki: 95 nM, EC50: 120 and 170 nM). NXPZ-2 dose-dependently attenuates Aβ[1-42]-induced cognitive disturbances, enhances neuronal number and function, and improves pathological alterations in the brain of Alzheimer’s disease (AD) mice. NXPZ-2 has potential for studies of Keap1-Nrf2 PPI inhibitors and AD-related disorders.
Web ID
– T64214
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H27N5O7S2
CAS Number
– 2254492-08-3
Molecular Weight
– C27H27N5O7S2
SMILES
– N(S(=O)(=O)C1=CC=C(OC)C=C1)(CC(N)=O)C=2C3=C(C(N(S(=O)(=O)C4=CC=C(N)C=C4)CC(N)=O)=CC2)C=CC=C3
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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