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AMG-548 hydrochloride

SKU T63371-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– AMG-548 hydrochloride is a selective, orally active p38α inhibitor with a Ki value of 0.5 nM, a slight selectivity for p38β (Ki=36 nM) and a 1000-fold selectivity for p38γ and p38δ. AMG 548 hydrochloride also effectively inhibits whole blood LPS-stimulated TNFα with an IC50 value of 3 nM. AMG-548 hydrochloride directly inhibited casein kinase 1 isoforms δ and ε, which in turn inhibited Wnt signaling.

Web ID

– T63371

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H28ClN5O

Molecular Weight

– C29H28ClN5O

SMILES

– #N/A

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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