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10-Formyl-5,8-dideazafolic acid
838 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– 10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate. Folate is a member of the B-vitamin family, which plays a supporting role in a number of key biochemical reactions in the body, including RNA and DNA synthesis. Made up of pteridine, para-aminobenzoic acid, and glutamate, 10-Formyl-5,8-dideazafolic acid is a compound that inhibits de novo folate metabolism. It induces cell cycle arrest at phase G(1)-S, disrupts repair of cells damaged by radiation, and induces apoptosis.
Web ID
– T62996
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H21N5O7
References
– Horita DA,et al. Modeling of interactions between functional domains of ALDH1LChem Biol Interact. 2017 Oct 1;276:23-30.
CAS Number
– 61038-31-1
Molecular Weight
– C22H21N5O7
Compound Purity
– 0.9604
SMILES
– Nc1nc(=O)c2cc(CN(C=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)ccc2[nH]1
Pathway
– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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