SEN177

SKU T61063-1 mg Category Brand:

Price range: 96 CAD through 1,214 CAD

Products Details

Product Description

– SEN177 shows the potential in the research of Huntington’s disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].

Web ID

– T61063

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H19FN6

CAS Number

– 2117405-13-5

Molecular Weight

– C18H19FN6

SMILES

– Cn1cnnc1C1CCN(CC1)c1ncccc1-c1ccc(F)nc1

Pathway

– Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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